What is diffuse large B-cell lymphoma (DLBCL)?

Diffuse large B-cell lymphoma, or DLBCL, is a type of aggressive lymphoma that affects B cells. B cells are white blood cells that protect your body from infection.

In DLBCL, B cells can grow and multiply uncontrollably

For illustrative purposes. Populations of cancerous cells differ from patient to patient.

Although DLBCL can occur at any age, its occurrence increases with age. Most people are first diagnosed between the ages of 65 and 74.

DLBCL can affect both men and women, although it is slightly more common in men.

The cause of DLBCL is unknown.

What does relapsed or refractory (R/R) mean?

Relapse happens when the cancer or the signs and symptoms of the cancer return after responding to previous treatment.

Refractory refers to a disease that has not responded to previous treatment.

Relapsed or refractory diffuse large B-cell lymphoma is often referred to as R/R DLBCL.

Additional resources

Treatment Guide: Learn more about POLIVY and relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL)

You can learn more about cancer by visiting the websites below:

American Cancer Society 1-800-ACS-2345 (1-800-227-2345)
CancerCare 1-800-813-HOPE (1-800-813-4673)
National Comprehensive Cancer Network www.nccn.org/patients


Genentech is neither affiliated with nor endorses any of these third-party organizations. We do not make any representation or guarantee as to the accuracy of the information on sites not controlled by Genentech. These links are provided for informational purposes only.