POLIVY is given in combination with a chemotherapy regimen. POLIVY plus bendamustine and a rituximab product (BR) is given on the first day of each treatment cycle. Bendamustine is given by itself on the second day of each cycle. Your doctor may have you take additional medicines ahead of time to prepare you for your infusions.
Typically, you will have 3 weeks before the next treatment cycle is given. However, your doctor will decide how long to wait between each cycle and how many cycles you need. Talk to your doctor about how you will receive POLIVY.
Some people may experience side effects during or after the infusion process. Please see Preparing for Infusion for more information about these reactions. If you have questions about dosing or the infusion process, talk to your doctor.
POLIVY is administered as an intravenous (IV) infusion (directly into the vein) in a clinic or infusion center. Talk to your healthcare team if you experience any side effects during or after the infusion.
90-minute first infusion
Your healthcare team will monitor you for a minimum of 90 minutes following your first dose.
30 minutes for every other infusion if the first dose went well
Your healthcare team will continue to monitor you for 30 minutes after the completion of follow-up doses.
Some therapies have a complicated preparation process, but POLIVY is available when you need it. POLIVY is ordered by your doctor and is usually given in a clinic or infusion center, not in a hospital.
POLIVY® is a prescription medicine used with other medicines, bendamustine and a rituximab product, to treat diffuse large B-cell lymphoma in adults who have progressed after at least 2 prior therapies.
The conditional approval of POLIVY is based on a type of response rate. There are ongoing studies to establish how well the drug works.
Everyone reacts differently to POLIVY therapy, so it’s important to know what the side effects are. Some people who have been treated with POLIVY have experienced serious to fatal side effects. Your doctor may stop or adjust your treatment if any serious side effects occur. Be sure to contact your healthcare team if there are any signs of these side effects.
Side effects seen most often
The most common side effects during treatment were
POLIVY may not be for everyone. Talk to your doctor if you are
These may not be all the side effects. Talk to your healthcare provider for more information about the benefits and risks of POLIVY treatment.
You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555.
Please see the full Prescribing Information for additional Important Safety Information.
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